Checkpoint 3

The goal was to engineer a contraption that could be either self-propelled – or at least require minimal interaction. Our solution, as can be seen in the above sketches, revolves around a tightly-threaded pole that mounts directly into the ground. The mechanism attaching to the pole is separated into two parts, which glide across each other using a ring of ball bearings. The lower half of the mechanism involves two spring-loaded latches on opposite sides of the pole, which hold the mechanism inside the threads while descending (ascension will be discussed shortly). Fan propellers would be mounted around the mechanism here. The upper half of the mechanism does not rotate. It houses a ring of copper coils and an outer ring of magnets that create an electromagnetic field, propelling the rotation. Above the coils is a UVA LED strip ringing the upper outside of the trap, to lure in mosquitoes. This light would be powered by several coin batteries, which insert into the mechanism and “click” into place under a protective silicone covering. Mounted above this mechanism would be several stabilizing bars that hold the top of the mosquito net. The net hangs down like a basket and creates a seal around the pole.

The key feature of this design is the spring-loaded latches which insert into the threads of the supporting pole. The weight of the contraption would slowly pull the fan along the threads down the poll, forcing the fan blades to rotate. When the fan reaches the bottom – presumably several times a day – strong cords that exit near the bottom of the poll would be pulled to hoist the fan back to the top. The latches are designed to retreat into the mechanism at this point, bypassing the threads for ascension. When the pulling chords are released, the latches hook into the nearest thread, and the fan again begins its fall.

Our final prototype will involve 3D-printed components so that we can see the mosquito trap in action, with working, moving parts.

Prototype Mock-up

To see our updated educational component, click here.

04/22-04/28 Update

Want to see our updates all in one spot? Click here.

Tasks Remaining for Monday Meeting:

  • none!

    Tasks Remaining for Wednesday Meeting:

  • none!

Tasks Completed:

  • Danielle – update References list
  • Taye – post further research on Dengue Survival kit see post
  • Franklin – post further research on Insect Repellent Lotion see post
  • Danielle – post further research on pricing and harmful aspects of Insecticide Lamp see post
  • Leila – post bath bomb solution see post
  • Taye – survival kit drawing
  • Taye – draft of Educational Poster see poster
  • Franklin – post survival kit write-up see post
  • Danielle – contraption solution write-up and drawing see post
  • Danielle – compile everyone’s submissions for Checkpoint 2
  • submit Checkpoint 2 on Blackboard by 2:30 PM

Upcoming Deadlines:

  • Individual CATME Peer Evaluations due Monday, April 22nd at 2:30 PM
  • Checkpoint 2 due Wednesday, April 24th at 2:30 PM

Checkpoint 2

Permethrin bath-bomb solution

This solution is a bath bomb containing the chemical permethrin.

Firstly, a bath bomb is a hard-packed mixture of ingredients which effervescence when it comes into contact with water and permethrin is a synthetic version of a chemical produced naturally by the chrysanthemum flower and is an insecticide. It is often put on clothes as a spray and it bonds to fabric killing ticks, mosquitoes, and insects that land on them.

This solution combines these two things to create a permethrin bath bomb. People would place this bath bomb into water, soak they clothes into the water and air the clothing. Once dry, the clothes will contain permethrin. The bath bombs would be distributed to people in small packets. With the bath bombs there will be reusable gloves and instructions on how to use the bath bombs. Furthermore, the education aspect will also include how to use the bath bombs and in community gathering areas, such as at local mosques, they can also discuss how to use these bath bombs. The information would include how many bath bombs to use, safety, how long to soak clothes for, etc.

Permethrin is the most effective chemical for this solution. Firstly, permethrin-treated clothes are still effective even after multiple washes. For example, a study illustrated that for the genus Aedes mosquitoes, that cause dengue, “the toxic effect of permethrin reduced biting rates by greater than 90% within the immediate area where subjects wore permethrin-treated uniforms for 9 hours.” (“The effectiveness of permethrin and deet, alone or in combination, for protection against Aedes taeniorhynchus,” 1984). This is ideal in Yemen as they are currently struggling with a water storage crisis and so cannot wash or treat their clothes with this chemical regularly so the long-lasting effect will benefit them greatly.

Furthermore, it is an inexpensive chemical. A large gallon cost between from 30 to 100 dollars. For example, a Martin’s Permethrin SFR Insecticide contains 36.8% of permethrin in 1.25 gallons. Thus, is not expensive to create small bath bombs. Moreover, the bath bombs will be diluted so it will not dangerous but still be effective, at most a 0.5% concentration.

Moreover, in terms of toxicity, Connecticut Department of Public Health, claimed that it “has low mammalian toxicity, is poorly absorbed through the skin, and is rapidly inactivated by the body… Skin reactions have been uncommon.” (Stafford C. K. III, 1999). Thus, the clothes would protect them without causing harm.

However, there are some limitations to this solution.

After using permethrin, the water must be discarded. This may pose a problem in Yemen, as the water is very scarce, and they may want to recycle it which would not be possible after using permethrin and so may decide simply not to use it. Furthermore, considering that Yemen is a very hot country the men and children may wear loose clothing or short sleeves making the solution ineffective as they will still be exposed to the mosquitoes. Moreover, although it is not toxic, the Environmental Protection Agency classifies it as a likely human carcinogen if consumed which may also pose some health risks. (“How Permethrin-treated Clothing Keeps You Safe”, 2018). Moreover, this will not only kill mosquitoes but also ticks and other insects which may cause harm to the ecosystem as untargeted organisms are being killed.

However, despite these limitations the solution is very simple, cheap and effective. Therefore, will be very beneficial in our particular context in Yemen.

Bath Bomb Sketch

Dengue Survival Kits

The Description of Dengue Survival Kits: Dengue surviving kits are a package of basic tools and supplies prepared in advanced as aids to the people suffering from emergency Dengue disease resulting from Aedes mosquito bites. These Dengue surviving kits include mosquito bed-nets, mosquito repellent lotions, mosquito repellent bracelets and others

The Cost of These Products: These products are inexpensive. For instance, Mosquito repellent lotions prices range from $4.00 to $29.00, 10 packs of mosquito repellent bracelets cost $9.99 and mosquito bed-nets cost $29.99. However, since we are working with WHO and other sponsoring organizations, we would be able to get financial support from these donor organizations to enable us to acquire these products for the people in Yemen for free of charge.

How to Use These Kits:

  • Mosquito Repellent Lotions: Pour the lotion into your palms and smear it gently on your face, around your chin and your eyebrow. Spread it around your neck, shoulders, torso (back and front), elbows, arms, fingers, thighs, knees, legs and the feet. Wait for at least 30 minutes for the lotion to dry on your face and all parts of your body before going to bed to avoid wiping out of the lotion from your body by the bed sheet. Close the lid of the lotion tightly after use to avoid leak out of the lotion. Keep the lotion out of reach of children before and after use.
  • Mosquito Repellent Bracelets: These bracelets contain non-toxic natural ingredients Citronella, Lemongrass and Geraniol that are proven to repel mosquitoes from coming into contact with humans. These bracelets are worn like wearing a wrist watch or a wrist band. Each bracelet worn on your wrist can last for 7 days before replacing it with a new one.
  • Mosquito Bed Net: Open the mosquito bed net on your bed and tuck it under your mattress to keep the mosquitoes out. Tuck the mosquito net over a crib under the mattress. Pull the mosquito net to cover the entire bed from the top to the floor to block any possible way of entry by the mosquitoes. If the mosquito bed net is sagging in towards the sleeping area, pull it tightly to the other objects and tie it to that to avoid choking a child on the bed.

How These Products Are Effective:

  • Mosquito Repellent Lotion: These lotions are effective in repelling Aedes mosquitoes from biting. However, a literature review by Lupi, Hatz and Schlagenhauf shows that it only lasts for 480 hours.
  • Mosquito Bracelets: These products are effective in repelling mosquitoes from coming into contact with humans. However, it only lasts for seven days. It needs a replacement every seven days.
  • Mosquito Bed Nets: These bed nets are effective in repelling mosquitoes because they offer the sleeper barriers protection against bites from mosquitoes. Research has shown that mosquito bed nets are an effective method of mosquito prevention. Mosquito bed nets helped to prevent approximately 663 million cases of mosquito-caused diseases over the period of 2000 to 2015.

The Limitations of The Use of These Dengue Survival Kits:

  • Mosquito Repellent Lotions: Easy to contaminate and stain the bed sheet, the pillows and other clothing materials on the bed. Bed sheets and pillows need to be washed frequently to avoid odor if the user sweats a lot during sleeping.
  • Mosquito Repellent Bracelets: Safe to use but lasts for only seven days. It must be replaced every seven days.
  • Mosquito Bed Nets: It needs frequent monitoring to ensure that it does not choke any child sleeping on the bed. It becomes unsafe to use it to protect against mosquito bites if part of it is torn.
Dengue Survival Kit

 

Self-propelled Mosquito Trap

One of our tentative solutions to the dengue crisis in Yemen is an extension of an existing contraption developed by the CDC, known as a CDC trap. The CDC trap is a mosquito trap initially designed to catch mosquitoes so that CDC researchers may study mosquito populations in a specific area and identify the illnesses they transmit. The CDC trap employs a small fan (powered by a 6V battery) mounted at the top of a net trap. A light and CO2 bait source are located just below the fan in order to attract mosquitoes, and the fan propels them down into the net trap where they eventually die of exhaustion (The VDCI Team, 2017).

Much like the CDC trap, our trap would utilize a light source as an attractant. A study published in Florida Entomologist suggests that blacklight is the most effective at luring mosquitoes in while simultaneously capturing the fewest “non-target insects” (University of Florida Institute of Food and Agricultural Sciences, 2015) . The two mosquito species responsible for transmitting dengue in Yemen, Aedes albopictus and Aedes aegypti, tend to be daytime biters, making visual attractants more effective. Thus, our trap would employ a blacklight to attract the mosquitoes.

The remaining parts of this solution are intended to trap and kill as many mosquitoes as possible. Using a small fan at the top would propel any nearby mosquitoes down into the trap. Portable, battery-powered fans can be found on Amazon.com for around $8-12 USD (“Amazon.com: O2COOL 5″ Portable Fan Battery Powered 1 Unit Grey: Home & Kitchen,” n.d.), (“Amazon.com: Cooler Master SickleFlow 120 – Sleeve Bearing 120mm Blue LED Silent Fan for Computer Cases, CPU Coolers, and Radiators: Electronics,” n.d.). A net with tight-nit mesh would be utilized below the fan to catch any mosquitoes. The entire trap would be coated in an insecticide to kill any mosquitoes that touch it but are not trapped by the fan and net. We have chosen to use Actellic 300CS because of its ability to kill pyrethroid-resistant mosquitoes and its ability to remain effective for up to 9 months outdoors (Hoppé, Hueter, Bywater, Wege, & Maienfisch, 2016).

Top-down Perspective View

 

Cross-Section Detail of Mechanism

The goal was to engineer a contraption that could be either self-propelled – or at least require minimal interaction. Our solution, as can be seen in the above sketches, revolves around a tightly-threaded pole that mounts directly into the ground. The mechanism attaching to the pole is separated into two parts, which glide across each other using a ring of ball bearings. The lower half of the mechanism involves two spring-loaded latches on opposite sides of the pole, which hold the mechanism inside the threads while descending (ascension will be discussed shortly). Fan propellers would be mounted around the mechanism here. The upper half of the mechanism does not rotate. It houses a ring of copper coils and an outer ring of magnets that create an electromagnetic field, propelling the rotation. Above the coils is a UVA LED strip ringing the upper outside of the trap, to lure in mosquitoes. This light would be powered by several coin batteries, which insert into the mechanism and “click” into place under a protective silicone covering. Mounted above this mechanism would be several stabilizing bars that hold the top of the mosquito net. The net hangs down like a basket and creates a seal around the pole.

The key feature of this design is the spring-loaded latches which insert into the threads of the supporting pole. The weight of the contraption would slowly pull the fan along the threads down the poll, forcing the fan blades to rotate. When the fan reaches the bottom – presumably several times a day – strong cords that exit near the bottom of the poll would be pulled to hoist the fan back to the top. The latches are designed to retreat into the mechanism at this point, bypassing the threads for ascension. When the pulling chords are released, the latches hook into the nearest thread, and the fan again begins its fall.

A tentative cost analysis has been done on some of the required materials. Actellic 300CS costs roughly $23 USD per bottle, although funding through organizations like NGenIRS have dropped the price to around $15 USD (President’s Malaria Initiative, 2017). One bottle of this insecticide could be used to treat hundreds of these mosquito traps, although that figure requires further analysis. We must perform additional research to identify the costs of the remaining required materials.

With further tweaks, this design is a feasible one. Partnered with our educational component, the people of Yemen would quickly appreciate the dangers that dengue-transmitting mosquitoes present. This trap would not take up valuable space inside of the home and requires little maintenance. The trap is modular by nature and would be easy to assemble when provided with text-free pictorial instructions. Many of the components that make up this trap could be constructed from affordable materials; the most expensive components will be the magnets and copper wire.

Decision Matrix: Choosing a Solution

 Mosquito TrapDengue Survival KitBath Bomb
(4) Cost144
(6) Longevity/Durability534
(9) Human Safety553
(10) Applicable to Yemen/Context555
(3) Environmental Safety553
(2) Ease of Distribution334
(5) Range of Impact533
(1) Learnability122
(7) Required Skills332
(8) Acceptability Factor555
Totals237228205

As a team, we decided on the ten most important factors that would determine whether a specific solution should be used. Once we had our list, we ranked them on a scale from 1-10, with 10 being “most important.” For each solution, we then ranked how well that “importance/relevance factor” applied on a 1-5 scale. The 10 factors and a brief description of each are listed below, in order of increasing importance.

  1. Learnability: How easy is it for our target population to learn how to implement this solution?
  2. Ease of distribution: Is it portable? Easily distributed?
  3. Environmental Safety: How harmful is it to the environment?
  4. Cost: How much does one unit cost?
  5. Range of Impact: How many people does a single unit protect? Is it per person? Per household?
  6. Longevity/Durability: How long does the solution last? Does it require maintenance?
  7. Required Skills: What are the skills required of our target population to be able to use this solution? Does it require any physical skills? Are they required to read accompanying safety documentation? Assembly instructions?
  8. Acceptability Factor/Willing to Implement: How willing is our target population to integrate this solution into their daily lives? Does it integrate well with their lifestyle?
  9. Human Safety: How safe is it for human use? Are there any risk factors?
  10. Applicable to Yemen/Context: Does this solution apply to our target population of Yemen? Can it be used in their current situation/environment?

An analysis of the decision matrix shows that the mosquito trap solution had the highest point value; therefore, this is the solution we will implement. Items to focus on moving forward include: a more in-depth cost analysis of materials, a feasibility study, and further development of our educational component.

Click here for the current draft of our educational poster.

 

References

7 Mosquito Repellent Plants – Garden Design. (n.d.). Retrieved April 24, 2019, from GardenDesign.com website: https://www.gardendesign.com/plants/mosquito-repellent.html

7 ways to prevent mosquito bites. (n.d.). Retrieved April 24, 2019, from https://www.onemedical.com/blog/live-well/7-ways-to-prevent-mosquito-bites

Almanac, O. F. (n.d.). Mosquito Repellents and Bite Remedies. Retrieved April 24, 2019, from Old Farmer’s Almanac website: https://www.almanac.com/content/how-deter-mosquitoes-and-treat-bug-bites

Amazon.com: Cooler Master SickleFlow 120 – Sleeve Bearing 120mm Blue LED Silent Fan for Computer Cases, CPU Coolers, and Radiators: Electronics. (n.d.). Retrieved April 23, 2019, from https://www.amazon.com/Cooler-Master-SickleFlow-120-Radiators/dp/B0026ZPFCK

Amazon.com: O2COOL 5″ Portable Fan Battery Powered 1 Unit Grey: Home & Kitchen. (n.d.). Retrieved April 23, 2019, from https://www.amazon.com/O2COOL-Portable-Battery-Powered-Unit/dp/B001B16VT6?ref_=fsclp_pl_dp_1

CDC. (2018, May 1). Mosquito Bites: Everyone is at Risk! Retrieved April 24, 2019, from Centers for Disease Control and Prevention website: https://www.cdc.gov/media/dpk/diseases-and-conditions/mosquito-borne-diseases/index.html

Hoppé, M., Hueter, O. F., Bywater, A., Wege, P., & Maienfisch, P. (2016). Evaluation of Commercial Agrochemicals as New Tools for Malaria Vector Control. CHIMIA International Journal for Chemistry, 70(10), 721–729. https://doi.org/10.2533/chimia.2016.721

Lupi, E., Hatz, C., & Schlagenhauf, P. (2013). The efficacy of repellents against Aedes, Anopheles, Culex and Ixodes spp. – a literature review. Travel Medicine and Infectious Disease, 11(6), 374–411. https://doi.org/10.1016/j.tmaid.2013.10.005

Maia, M. F., Kliner, M., Richardson, M., Lengeler, C., & Moore, S. J. (2018). Mosquito repellents for malaria prevention. The Cochrane Database of Systematic Reviews, (2). https://doi.org/10.1002/14651858.CD011595.pub2

Permethrin-Treated Clothing for Insect Protection. (2018, August 15). Retrieved April 24, 2019, from Modern Pest website: https://www.modernpest.com/blog/how-permethrin-treated-clothing-keeps-you-safe/

Schreck, C. E., Haile, D. G., & Kline, D. L. (1984). The effectiveness of permethrin and deet, alone or in combination, for protection against Aedes taeniorhynchus. The American Journal of Tropical Medicine and Hygiene, 33(4), 725–730.

The VDCI Team. (2017). Mosquito Surveillance Traps: Are They All The Same? Retrieved April 17, 2019, from http://www.vdci.net/blog/mosquito-surveillance-traps-are-they-all-the-same

Tick Bite Prevention. (2005, September 12). Retrieved April 24, 2019, from https://web.archive.org/web/20050912070432/http:/www.dph.state.ct.us/BCH/infectiousdise/tickborne/tick.htm#Permethrin

Webb, C. (n.d.). Health Check: do wrist bands work to repel mozzies? Retrieved April 24, 2019, from The Conversation website: http://theconversation.com/health-check-do-wrist-bands-work-to-repel-mozzies-50186

Self-Propelled Mosquito Trap

One of our tentative solutions to the dengue crisis in Yemen is an extension of an existing contraption developed by the CDC, known as a CDC trap. The CDC trap is a mosquito trap initially designed to catch mosquitoes so that CDC researchers may study mosquito populations in a specific area and identify the illnesses they transmit. The CDC trap employs a small fan (powered by a 6V battery) mounted at the top of a net trap. A light and CO2 bait source are located just below the fan in order to attract mosquitoes, and the fan propels them down into the net trap where they eventually die of exhaustion (The VDCI Team, 2017).

Much like the CDC trap, our trap would utilize a light source as an attractant. A study published in Florida Entomologist suggests that blacklight is the most effective at luring mosquitoes in while simultaneously capturing the fewest “non-target insects” (University of Florida Institute of Food and Agricultural Sciences, 2015) . The two mosquito species responsible for transmitting dengue in Yemen, Aedes albopictus and Aedes aegypti, tend to be daytime biters, making visual attractants more effective. Thus, our trap would employ a blacklight to attract the mosquitoes.

The remaining parts of this solution are intended to trap and kill as many mosquitoes as possible. Using a small fan at the top would propel any nearby mosquitoes down into the trap. Portable, battery-powered fans can be found on Amazon.com for around $8-12 USD (“Amazon.com: O2COOL 5″ Portable Fan Battery Powered 1 Unit Grey: Home & Kitchen,” n.d.), (“Amazon.com: Cooler Master SickleFlow 120 – Sleeve Bearing 120mm Blue LED Silent Fan for Computer Cases, CPU Coolers, and Radiators: Electronics,” n.d.). A net with tight-nit mesh would be utilized below the fan to catch any mosquitoes. The entire trap would be coated in an insecticide to kill any mosquitoes that touch it but are not trapped by the fan and net. We have chosen to use Actellic 300CS because of its ability to kill pyrethroid-resistant mosquitoes and its ability to remain effective for up to 9 months outdoors (Hoppé, Hueter, Bywater, Wege, & Maienfisch, 2016).

Top-down Perspective View

 

Cross-Section Detail of Mechanism

The goal was to engineer a contraption that could be either self-propelled – or at least require minimal interaction. Our solution, as can be seen in the above sketches, revolves around a tightly-threaded pole that mounts directly into the ground. The mechanism attaching to the pole is separated into two parts, which glide across each other using a ring of ball bearings. The lower half of the mechanism involves two spring-loaded latches on opposite sides of the pole, which hold the mechanism inside the threads while descending (ascension will be discussed shortly). Fan propellers would be mounted around the mechanism here. The upper half of the mechanism does not rotate. It houses a ring of copper coils and an outer ring of magnets that create an electromagnetic field, propelling the rotation. Above the coils is a UVA LED strip ringing the upper outside of the trap, to lure in mosquitoes. This light would be powered by several coin batteries, which insert into the mechanism and “click” into place under a protective silicone covering. Mounted above this mechanism would be several stabilizing bars that hold the top of the mosquito net. The net hangs down like a basket and creates a seal around the pole.

The key feature of this design is the spring-loaded latches which insert into the threads of the supporting pole. The weight of the contraption would slowly pull the fan along the threads down the poll, forcing the fan blades to rotate. When the fan reaches the bottom – presumably several times a day – strong cords that exit near the bottom of the poll would be pulled to hoist the fan back to the top. The latches are designed to retreat into the mechanism at this point, bypassing the threads for ascension. When the pulling chords are released, the latches hook into the nearest thread, and the fan again begins its fall.

A tentative cost analysis has been done on some of the required materials. Actellic 300CS costs roughly $23 USD per bottle, although funding through organizations like NGenIRS have dropped the price to around $15 USD (President’s Malaria Initiative, 2017). One bottle of this insecticide could be used to treat hundreds of these mosquito traps, although that figure requires further analysis. We must perform additional research to identify the costs of the remaining required materials.

With further tweaks, this design is a feasible one. Partnered with our educational component, the people of Yemen would quickly appreciate the dangers that dengue-transmitting mosquitoes present. This trap would not take up valuable space inside of the home and requires little maintenance. The trap is modular by nature and would be easy to assemble when provided with text-free pictorial instructions. Many of the components that make up this trap could be constructed from affordable materials; the most expensive components will be the magnets and copper wire.

References

Amazon.com: Cooler Master SickleFlow 120 – Sleeve Bearing 120mm Blue LED Silent Fan for Computer Cases, CPU Coolers, and Radiators: Electronics. (n.d.). Retrieved April 23, 2019, from https://www.amazon.com/Cooler-Master-SickleFlow-120-Radiators/dp/B0026ZPFCK

Amazon.com: O2COOL 5″ Portable Fan Battery Powered 1 Unit Grey: Home & Kitchen. (n.d.). Retrieved April 23, 2019, from https://www.amazon.com/O2COOL-Portable-Battery-Powered-Unit/dp/B001B16VT6?ref_=fsclp_pl_dp_1

CDC. (2018, May 1). Mosquito Bites: Everyone is at Risk! Retrieved April 24, 2019, from Centers for Disease Control and Prevention website: https://www.cdc.gov/media/dpk/diseases-and-conditions/mosquito-borne-diseases/index.html

Hoppé, M., Hueter, O. F., Bywater, A., Wege, P., & Maienfisch, P. (2016). Evaluation of Commercial Agrochemicals as New Tools for Malaria Vector Control. CHIMIA International Journal for Chemistry, 70(10), 721–729. https://doi.org/10.2533/chimia.2016.721

The VDCI Team. (2017). Mosquito Surveillance Traps: Are They All The Same? Retrieved April 17, 2019, from http://www.vdci.net/blog/mosquito-surveillance-traps-are-they-all-the-same

Solar-Powered, Insecticide-Coated Mosquito Trap: Cost Analysis

Insecticide

Actellic 300CS

  • starred countries used ONLY Actellic as an insecticide for both 2016 and 2017

Fan

Existing Full Solution Ideas

References

Actellic 300CS. (2018, April 12). Retrieved April 23, 2019, from Syngenta website: https://www.syngentappm.com/product/crop-protection/vector-control/actellicr300cs

digitalaudiotapeFollow. (n.d.). A Cheap & No Maintenance LED Fan Mosquito Trap. Retrieved April 23, 2019, from Instructables website: https://www.instructables.com/id/A-Cheap-No-Maintenance-LED-Fan-Mosquito-Trap/

President’s Malaria Initiative. PMI IRS Country Programs: 2017 Comparative Cost Analysis [PDF file]. Retrieved from https://www.pmi.gov/docs/default-source/default-document-library/implementing-partner-reports/africa-indoor-residual-spraying-project-pmi-irs-country-programs-2017-comparative-cost-analysis.pdf?sfvrsn=4

Insecticide-Coated Solar-Powered Lamp: Initial Research

https://www.malariaconsortium.org/pages/110.htm

(“Malaria Consortium – Long Lasting Insecticidal Nets,” n.d.)

  • LLINs treated in the factory
  • insecticide lasts at least 20 washes (lab tested)
  • lasts 3 years in the field
  • current LLIN frontrunners use the following key ingredients:
    • 2% permethrin (used by Olyset Net)
    • deltamethrin (used by PermaNet)
    • alphacypermenthrin (Interceptor)

 

http://www.mosquitoworld.net/mosquito-control/insecticide/

(“Mosquito Insecticide,” n.d.)

  • 2 popular insecticides:
    • Malathion
      • organophosphate
      • often used to treat crops against wide variety of insects
      • sprayed directly on vegetation or as a fog treatment on yard (5% solution)
      • poses no threats to humans or wildlife in these amounts
    • Permethrin
      • pyrethroid
      • synthetic for of natural insecticide found in chrysanthemum flowers
      • applied as a mist (mixed with oil or water)
      • not harmful to humans or animals in small amounts
      • toxic to fish and bees
    • both kill mosquitoes by disrupting their CNSs
    • both work for several days but break down over time, especially in rain
  • repeated use can lead to insecticide resistance in mosquito populations

 

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)30427-6/fulltext

(Protopopoff et al., 2018)

  • Actellic 300CS by Syngenta of Switzerland is effective for up to 10 months when used for indoor residual spraying
    • organophosphate pirimipohs-methyl

 

https://www.ingentaconnect.com/contentone/scs/chimia/2016/00000070/00000010/art00008?crawler=true

(Hoppé, Hueter, Bywater, Wege, & Maienfisch, 2016)

  • VERY USEFUL STUDY ON AGROCHEMICALS FOR VECTOR CONTROL
  • intended for pyrethroid-resistant mosquitoes after IRS (indoor residual spraying)
  • results in at least 9 months of control vs. 3 months from current pyrethroid alternatives

 

https://www.sciencedaily.com/releases/2015/06/150609092805.htm

(“Light trap lures more mosquitoes, fewer bugs you don’t need to kill,” n.d.)

  • blacklight traps are most effective at trapping mosquitoes and simultaneously capturing the fewest “non-target insects”
  • (study published in Florida Entomologist)

“Black lights produce a light that is considerably more attractive to insects,” Kaufman said. “Humans cannot see ‘UV,’ so what we are really seeing in a ‘black light’ or bug zapper light are the wavelengths that don’t quite make it to the UV spectrum. Insects, however, see it quite clearly, and many like it.
“The light traps essentially catch anything that is small enough to get sucked in when they get close to the mouth at the top of the trap,” he said.

 

http://www.mosquitoworld.net/mosquito-control/traps/

(“Mosquito Traps,” n.d.)

  • “…just one or two of these ingenious devices can kill thousands of mosquitoes and all but wipe out a local population”
  • many traps use a combination of lighting displays and artificial smells to attract mosquitoes
  • mosquitoes detect C02, octenol, and other chemical odors
  • Mosquito Magnet and Skeetervac burn propane for power and to release C02.
  • certain species respond in different ways
    • Asian tiger mosquito (transmits dengue!) is a daytime biter; more responsive to visual attractants
  • “can take as much as two months to kill enough female mosquitoes to collapse local mosquito populations”
  • according to university study, Mega-Catch Ultra mosquito trap outperformed competitors
    • $900!!!

 

http://npic.orst.edu/pest/mosquito/mosqcides.html

(“Pesticides Used in Mosquito Control,” n.d.)

  • larvicides – applied directly to water to control mosquito larvae
  • adulticides – used in fogging and spraying to control adult mosquitoes
  • synergists – not toxic to mosquitoes themselves but make adulticides more effective
  • resmethrin
    • “In the soil, resmethrin has a half-life of 30 days and is primarily broken down by sunlight. Resmethrin does not mix well with water and binds tightly to the soil, so resmethrin will not be likely to move through the soil. These characteristics make it unlikely for resmethrin to get into groundwater. Resmethrin does not significantly evaporate into the air from the surface of soil or water.

      Researchers applied resmethrin to surfaces exposed to sunlight and observed a half-life of 20-90 minutes. When researchers studied resmethrin indoors, resmethrin broke down within a few hours from exposure to natural sunlight.

      Resmethrin is not toxic to plants. Researchers applied resmethrin to tomato and lettuce plants and found that 55 to 82% of resmethrin was broken down within 2 hours. No resmethrin remained on the plants after 5 days.” (“Pesticides Used in Mosquito Control,” n.d.)

  • permethrin – LIKELY CARCINOGEN according to US EPA

 

http://www.vdci.net/blog/mosquito-surveillance-traps-are-they-all-the-same

(The VDCI Team, 2017)

  • BG-Sentinel Trap
    • for Aedes albopictus and Aedes aegypti
    • made of a tarp-like material, size of 5-gallon bucket
    • utilizes an attractant such as Octenol lure, human scent lure, or CO2
    • funnel at the top leads mosquitoes to an electric fan (battery powered) that pulls them into a collection net
  • CDC Light Trap
    • powered by a 6V battery with a motorized fan and mosquito collection cup
    • portable
    • accompanied by a small light and CO2 bait source
    • drawn in at the top, forced downward by the fan into the inescapable collection net
    • better for nighttime-active species

References

Hoppé, M., Hueter, O. F., Bywater, A., Wege, P., & Maienfisch, P. (2016). Evaluation of Commercial Agrochemicals as New Tools for Malaria Vector Control. CHIMIA International Journal for Chemistry, 70(10), 721–729. https://doi.org/10.2533/chimia.2016.721

Light trap lures more mosquitoes, fewer bugs you don’t need to kill. (n.d.). Retrieved April 17, 2019, from ScienceDaily website: https://www.sciencedaily.com/releases/2015/06/150609092805.htm

Malaria Consortium – Long Lasting Insecticidal Nets. (n.d.). Retrieved April 17, 2019, from https://www.malariaconsortium.org:443/pages/110.htm

Mosquito Insecticide. (n.d.). Retrieved April 17, 2019, from Mosquito World website: http://www.mosquitoworld.net/mosquito-control/insecticide/

Mosquito Traps. (n.d.). Retrieved April 17, 2019, from Mosquito World website: http://www.mosquitoworld.net/mosquito-control/traps/

PermaNet is the leading long-lasting insecticide-treated bed net. (n.d.). Retrieved April 17, 2019, from https://www.vestergaard.com/our-products/permanet

Pesticides Used in Mosquito Control. (n.d.). Retrieved April 17, 2019, from http://npic.orst.edu/pest/mosquito/mosqcides.html

Protopopoff, N., Mosha, J. F., Lukole, E., Charlwood, J. D., Wright, A., Mwalimu, C. D., … Rowland, M. (2018). Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two factorial design trial. The Lancet, 391(10130), 1577–1588. https://doi.org/10.1016/S0140-6736(18)30427-6

The VDCI Team. (2017, February 23). Mosquito Surveillance Traps: Are They All The Same? Retrieved April 17, 2019, from http://www.vdci.net/blog/mosquito-surveillance-traps-are-they-all-the-same

Prevention Research

https://www.cdc.gov/features/stopmosquitoes/index.html

https://www.cdc.gov/chikungunya/pdfs/fs_mosquito_bite_prevention_us.pdf

  • use an EPA-registered insect repellent (safe and effective, even from pregnant and breastfeeding women)
    • reapply every few hours, per instructions
    • don’t spray on skin under clothes
    • apply sunscreen first, then insect repellent
    • no OLE or PMD on children under 3
    • key ingredients
      • DEET
      • Picaridin (AKA KBR 3023 and icaridin)
      • IR3535
      • Oil of lemon eucalyptus (OLE)
      • Para-menthane-diol (PMD)
      • 2-undecanone
  • wear long-sleeved shirts and long pants
    • permethrin-treated clothes protect after multiple washings
  • wear light colors
  • wear shoes/foot protection (mosquitoes are attracted to skin odor)
  • use window/door screens or a mosquito bed net
  • biting habits of Aedes aegypti and Aedes albopictus: primarily daytime, sometimes at night

https://bestlifeonline.com/avoid-mosquito-bites/

  • basil is toxic to mosquito larvae
  • burning thyme is 85-90% effective at repelling mosquitoes
  • use fans

 

https://www.scientificamerican.com/article/genetically-engineered-mosquitoes/

  • genetically engineered mosquitoes have been released in the Cayman Islands, Malaysia, and Brazil to counteract dengue
  • developed by Oxitec
  • targeting Dengue because it is only 1 subspecies of mosquito

References

CDC. (n.d.). Mosquito Bite Prevention (United States) [PDF file]. Retrieved from https://www.cdc.gov/chikungunya/pdfs/fs_mosquito_bite_prevention_us.pdf

CDC. (2018, March 19). Mosquito Bites. Retrieved April 17, 2019, from Centers for Disease Control and Prevention website: http://www.cdc.gov/features/stopmosquitoes/

Genetically Engineered…Mosquitoes? (n.d.). Retrieved April 17, 2019, from Scientific American website: https://www.scientificamerican.com/article/genetically-engineered-mosquitoes/

BestLifeOnline.com (2018, May 9). 20 Genius Tricks to Avoid Getting Bitten by Mosquitos. Retrieved April 17, 2019, from Best Life website: https://bestlifeonline.com/avoid-mosquito-bites/

04/15-04/21 Update

Want to see our updates all in one spot? Click here.

Tasks Remaining for Monday Meeting:

  • Danielle – update References list

    Tasks Remaining for Wednesday Meeting:

    • Taye – post research on Dengue Survival Kit
    • Franklin – post research on Insect Repellent Lotion
    • Leila – post research on clothes-washing practices; Insect-Repelling Bath Bombs
    • Danielle – update References list
    • Taye – post further research on Dengue Survival Kit
    • Danielle – post further research on pricing and harmful aspects of Insecticide Lamp
    • Leila – post further research on safety aspects of Bath Bombs
    • Franklin – post further research on engineering aspect of Insect Repellent Lotion

Tasks Completed:

  • Danielle – post research on Insecticide-Coated Solar-Powered Lamp see post
  • Danielle – post initial prevention mechanism research see post
  • Taye – post initial prevention mechanism research see post
  • Leila – post initial prevent mechanism research see post

Upcoming Deadlines:

  • Individual CATME Peer Evaluations due Monday, April 15th at 2:30 PM
  • Individual CATME Peer Evaluations due Monday, April 22nd at 2:30 PM
  • Checkpoint 2 due Wednesday, April 24th at 2:30 PM

Checkpoint 1

Dengue is a vector-borne viral infection that affects many parts of the world. With up to 100 million infections occurring annually, dengue has placed nearly half of the world’s population at risk. Dengue causes severe, flu-like symptoms and can sometimes progress to “severe dengue,” formally known as “hemorrhagic fever.” First identified in the 1950s, today it is known to majorly affect Asian and Latin American countries. Severe dengue is a leading cause of death and hospitalization in these areas. Dengue thrives in poorer urban and suburban areas but has been documented in wealthier tropical and subtropical countries, as well (“WHO | What is dengue?,” n.d.).

Our team is focused on the effects of dengue specifically in Yemen. Located on the Arabian Peninsula, Yemen has become plagued by dengue fever for several reasons. First and foremost, Yemen’s climate, which includes a prolonged rainy season, results in standing water – a favorite breeding spot for mosquitos (Maged Ahmed Al-garadi, 2015). Additionally, Yemen has been plagued by civil war since 2015, perpetuating the country’s poor infrastructure (Yemen country profile, 2019). The war has forced Yemen to funnel resources into other areas, neglecting to effectively monitor and control the spread of the virus. The inherently poor population of Yemen lacks the knowledge of how to combat and treat dengue (Maged Ahmed Al-garadi, 2015). Many communities have poor sanitation practices, perpetuating the spread of dengue.

As a team, we determined five problems present in Yemen that tie into the country’s dengue pandemic. One issue is the lack of vector prevention mechanisms. The WHO adopted a 5-year plan to increase the “preparedness and response activities for dengue fever prevention and control,” but their efforts are primarily focused on increasing and strengthening surveillance and detection. Just a small element of their efforts focus on vector-control through insecticide spraying (“WHO EMRO | WHO develops national strategy for dengue prevention and control | Yemen-news | Yemen,” n.d.). The Yemeni government is presently enveloped in civil war and gives little attention to providing its population prevention mechanisms.

A second issue present in Yemen is poor water infrastructure, particularly regarding water storage. Ongoing war has led to a “breakdown in safe water supply and sanitation services” (Shadoul & Taha, 2015). This poor infrastructure results in water shortages, forcing many residents to store water in open containers in and around the home, leading to the gathering of mosquitoes (“Drinking water systems under repeated continuous attack in Yemen [EN/AR] – Yemen,” n.d.). A third issue concerns the sanitation conditions present in Yemen. Again, due to civil war, conditions in Yemeni cities are poor. Mounds of uncollected garbage line the streets. This trash, combined with untreated sewage and the Arabian heat, has created the perfect storm for dengue-carrying mosquitoes to flourish (Burki, 2016).

A fourth issue plaguing the population of Yemen is indoor air pollution. Domestic use of biomass fuels increases the amount of indoor air pollution and heat in a household and structure. As a result, we hypothesized that the warmer climate in the house would attract mosquitoes, which thus increases the potential of any inhabitants to be infected with dengue. However, the article written by Biran, Smith, Lines, Ensink, and Cameron indicates that the resulting smoke and smog from burning biomass acts as a natural repellant of mosquitoes.

Our final issue of note, briefly touched on previously, is that of open water containers. Open containers with standing water need to be scrubbed at least weekly to minimize mosquito breeding. Mosquito larvae attach to the sides of the container and can survive there without surrounding water for up to 8 months. As a result, just emptying the water will not stop the larvae from hatching and maturing and later infecting inhabitants with dengue (“Zika, Mosquitoes, and Standing Water | | Blogs | CDC,” n.d.).

After concluding our preliminary research on these five issues, we came together to narrow the list down to a single issue. We created a decision matrix to help with this process.

Problem Decision Matrix

 Protection MechanismsWater StorageSanitationIndoor Air PollutionStanding Water
(1) Prior Knowledge52553
(2) Ease of Research52312
(3) Significance53415
(4) Control52152
Totals5023273030

We chose four determining factors on which to rank each issue: our prior knowledge, ease of research, significance (or “does it matter?”), and control (or “can it even be done?”). We first gave weights to these factors, with four being most important and one being least important. Using a scale (from 1 to 5), we then went item by item, ranking each of the five issues on every factor. For example, our research found that indoor air pollution has very little impact on the high occurrence of dengue in Yemen; thus, it received the lowest significance rating. Standing water, on the other hand, proved to be a major contributor to high mosquito populations, so it received the highest significance rating.

As can be seen in our Totals column, the issue of lacking protection mechanisms stood out as the front-runner, receiving a rank of 5 in each category. Our prior knowledge of the subject is relatively high, having personal experience with various tools  such as mosquito nets, preventative clothing, and insecticide sprays. This issue is relatively easy to research, as documentation on the matter appears to be abundant. The lack of protection mechanisms available to the Yemeni population carries a high significance in regard to the rising count of residents contracting dengue. Finally, this issue can be “controlled,” or at least lessened. Moving forward, our team will focus on developing several practical engineering-based solutions to address this problem.

References:

Biran, A., Smith, L., Lines, J., Ensink, J., & Cameron, M. (2007). Smoke and malaria: are interventions to reduce exposure to indoor air pollution likely to increase exposure to mosquitoes? Transactions of the Royal Society of Tropical Medicine and Hygiene, 101(11), 1065–1071. https://doi.org/10.1016/j.trstmh.2007.07.010

Burki, T. (2016). Yemen’s neglected health and humanitarian crisis. The Lancet, 387(10020), 734–735. https://doi.org/10.1016/S0140-6736(16)00389-5

Drinking water systems under repeated continuous attack in Yemen [EN/AR] – Yemen. (n.d.). Retrieved April 9, 2019, from ReliefWeb website: https://reliefweb.int/report/yemen/drinking-water-systems-under-repeated-continuous-attack-yemen-enar

Maged Ahmed Al-garadi, د. م. ا. ا. (2015). Epidemiological review of dengue fever in Yemen. International Journal of Advanced Research, 3, 1578–1584.

Shadoul, A., Taha, A. (2015). Yemen Conflict Report. WHO. Retrieved from http://www.emro.who.int/images/stories/yemen/WHO_Yemen_sitrep_no8_7_June_2015.pdf

WHO | What is dengue? (n.d.). Retrieved April 9, 2019, from WHO website: http://www.who.int/denguecontrol/disease/en/

WHO EMRO | WHO develops national strategy for dengue prevention and control | Yemen-news | Yemen. (n.d.). Retrieved April 9, 2019, from http://www.emro.who.int/yem/yemen-news/who-develops-national-strategy-for-dengue-prevention-and-control.html

Yemen country profile. (2019, February 18). Retrieved from https://www.bbc.com/news/world-middle-east-14704852

Zika, Mosquitoes, and Standing Water | | Blogs | CDC. (n.d.). Retrieved April 9, 2019, from https://blogs.cdc.gov/publichealthmatters/2016/03/zikaandwater/

Presence of Vector Prevention Mechanisms in Yemen

According to the WHO, the two most successful vector control methods are insecticide-treated nets (ITNs) and indoor residual spraying (IRS) (“WHO | Global report on insecticide resistance in malaria vectors: 2010–2016,” n.d.). UNICEF is the world’s top buyer of long-lasting insecticidal nets (LLINs) which require no further treatment during the net’s lifespan (“Mosquito nets | Supplies and Logistics | UNICEF,” n.d.). A study done by the WHO determined that the presence of a mosquito net at all – regardless of whether or not it had been treated with insecticides – significantly lowered infection rates. Something to note, however, is that treated nets have the ability to kill mosquitos as well as keep them out, thus increasing their efficacy (“WHO | Five-year WHO investigation shows that LLINs remain a highly effective tool in the malaria fight,” n.d.). Current vector-prevention practices being implemented in Yemen by the WHO fail to include ITNs or LLINs, with prevention and control focusing on surveillance and early warning systems (“WHO EMRO | WHO develops national strategy for dengue prevention and control | Yemen-news | Yemen,” n.d.).

 

Sources:

Mosquito nets | Supplies and Logistics | UNICEF. (n.d.). Retrieved April 8, 2019, from https://www.unicef.org/supply/index_39977.html

WHO | Five-year WHO investigation shows that LLINs remain a highly effective tool in the malaria fight. (n.d.). Retrieved April 8, 2019, from https://www.who.int/malaria/news/2016/llins-effective-tool-malaria-fight/en/

WHO | Global report on insecticide resistance in malaria vectors: 2010–2016. (n.d.). Retrieved April 8, 2019, from https://www.who.int/malaria/publications/atoz/9789241514057/en/

WHO EMRO | WHO develops national strategy for dengue prevention and control | Yemen-news | Yemen. (n.d.). Retrieved April 9, 2019, from http://www.emro.who.int/yem/yemen-news/who-develops-national-strategy-for-dengue-prevention-and-control.html